energy production* neurological function* homocysteine metabolism*
MethylFolatePluswithshadow
Methyl Folate Plus™ was formulated with two bioavailable forms of folate, L-5 Methyltetrahydrofolate and folinic acid, plus a synergistic combination of bioavailable vitamins B2 and B3 (Niacin). It was designed to support cognitive function, neurotransmitter balance, healthy mood, cellular energy production, and protein and amino acid metabolism.*
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Methylation Complete™ allows maximum delivery of B12, B6, and 5-MTHF (folate) to the nervous and immune systems. Fast-dissolving tablets allow for quick release into the bloodstream. They may be especially beneficial for those who are vegetarian or have gastrointestinal issues due to aging, illness, surgery, or a methylation deficiency. Improved methylation has many benefits for the immune and nervous systems.*
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MethylationTopicalwithshadow
Methylation Pro Topical is targeted to promote optimal cellular functioning and maximize the efficiency of the methylation cycle.*
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Why Does Methylation Matter?

Think of methylation as one of your body's communication systems. It helps regulate how nutrients are used, supports normal cellular function, and plays a role in producing important compounds like neurotransmitters and antioxidants.

Energy Production

Bioactive B vitamins help your cells efficiently convert nutrients into usable energy.*

Brain & Nervous System

System Health Methylation contributes to the production of neurotransmitters that support mood, focus, and cognitive function.*

Detoxification

Healthy methylation supports the body's natural detoxification processes and antioxidant production.*

Cardiovascular Health

Methylation helps maintain healthy homocysteine metabolism, an important marker of cardiovascular wellness.*

DNA Health

Folate-dependent methylation plays an essential role in DNA synthesis and normal cellular repair.*

How to Choose the Right Methylation Supplement

Neurobiologix methylation supplements are physician-formulated with bioactive folate and B vitamins, offering options from single-nutrient support to comprehensive daily formulas.

Methylation Complete

Best For:

Individuals wanting comprehensive daily methylation support.

Highlights:

  • ✓ Complete methylation formula
  • ✓ Active folate plus bioavailable B6 and two forms of B12
  • ✓ Dissolvable, chewable tablets for rapid absorption
  • ✓ Supports energy production, neurological health, and detoxification*
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Methylation Pro Topical - Cream

Best For:

Individuals who prefer a topical delivery system.

Highlights:

  • ✓ Topical bioactive B-vitamin cream
  • ✓ Contains active folate, B6, B12, Vitamin D3, and Vitamin K1
  • ✓ Easy daily application
  • ✓ Ideal for those looking for an alternative to oral supplementation
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What Customers Are Saying

★★★★★

"I noticed an increase in energy from the very first dose. My integrative doctor recommended it, and it's become part of my daily routine."

★★★★★

"I can absolutely tell a difference when I take this consistently. My anxiety feels calmer, and my energy improves throughout the day."

★★★★★

"My hematologist recommended this formula, and my blood levels have been excellent ever since."

★★★★★

“I've taken these for years. Missing them for even a week reminded me how much they help."

★★★★★

"After three months, we've seen a significant improvement in my husband's overall health. We'll continue using this product."

What is methylation?
What is MTHFR?
Why is active folate important?
What is homocysteine?
Which methylation supplement should I choose?
Can I take methylation supplements if I have an MTHFR mutation?